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FocalScan: Scanning for altered genes in cancer based on coordinated DNA and RNA change
Somatic genomic copy-number alterations can lead to transcriptional activation or inactivation of tumor driver or suppressor genes, contributing to the malignant properties of cancer cells. Selection for such events may manifest as recurrent amplifications or deletions of size-limited (focal) region...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100559/ https://www.ncbi.nlm.nih.gov/pubmed/27474725 http://dx.doi.org/10.1093/nar/gkw674 |