An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targeting

The CRISPR/Cas9 system is a powerful genome editing tool and has been widely used for biomedical research. However, many challenges, such as off-target effects and lack of easy solutions for multiplex targeting, are still limiting its applications. To overcome these challenges, we first developed a...

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Detalles Bibliográficos
Autores principales: Cao, Jian, Wu, Lizhen, Zhang, Shang-Min, Lu, Min, Cheung, William K.C., Cai, Wesley, Gale, Molly, Xu, Qi, Yan, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100567/
https://www.ncbi.nlm.nih.gov/pubmed/27458201
http://dx.doi.org/10.1093/nar/gkw660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100567/
https://www.ncbi.nlm.nih.gov/pubmed/27458201
http://dx.doi.org/10.1093/nar/gkw660

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