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The structure of the pleiotropic transcription regulator CodY provides insight into its GTP-sensing mechanism

GTP and branched-chain amino acids (BCAAs) are metabolic sensors that are indispensable for the determination of the metabolic status of cells. However, their molecular sensing mechanism remains unclear. CodY is a unique global transcription regulator that recognizes GTP and BCAAs as specific signal...

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Detalles Bibliográficos
Autores principales: Han, Ah-reum, Kang, Hye-Ri, Son, Jonghyeon, Kwon, Do Hoon, Kim, Sulhee, Lee, Woo Cheol, Song, Hyun Kyu, Song, Moon Jung, Hwang, Kwang Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100569/
https://www.ncbi.nlm.nih.gov/pubmed/27596595
http://dx.doi.org/10.1093/nar/gkw775