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The structure of the pleiotropic transcription regulator CodY provides insight into its GTP-sensing mechanism
GTP and branched-chain amino acids (BCAAs) are metabolic sensors that are indispensable for the determination of the metabolic status of cells. However, their molecular sensing mechanism remains unclear. CodY is a unique global transcription regulator that recognizes GTP and BCAAs as specific signal...
Autores principales: | Han, Ah-reum, Kang, Hye-Ri, Son, Jonghyeon, Kwon, Do Hoon, Kim, Sulhee, Lee, Woo Cheol, Song, Hyun Kyu, Song, Moon Jung, Hwang, Kwang Yeon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100569/ https://www.ncbi.nlm.nih.gov/pubmed/27596595 http://dx.doi.org/10.1093/nar/gkw775 |
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