Transcription of telomeric DNA leads to high levels of homologous recombination and t-loops

The formation of DNA loops at chromosome ends (t-loops) and the transcription of telomeres producing G-rich RNA (TERRA) represent two central features of telomeres. To explore a possible link between them we employed artificial human telomeres containing long arrays of TTAGGG repeats flanked by the...

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Detalles Bibliográficos
Autores principales: Kar, Anirban, Willcox, Smaranda, Griffith, Jack D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100571/
https://www.ncbi.nlm.nih.gov/pubmed/27608724
http://dx.doi.org/10.1093/nar/gkw779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100571/
https://www.ncbi.nlm.nih.gov/pubmed/27608724
http://dx.doi.org/10.1093/nar/gkw779

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