Novel m4C modification in type I restriction-modification systems

We identify a new subgroup of Type I Restriction-Modification enzymes that modify cytosine in one DNA strand and adenine in the opposite strand for host protection. Recognition specificity has been determined for ten systems using SMRT sequencing and each recognizes a novel DNA sequence motif. Previ...

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Detalles Bibliográficos
Autores principales: Morgan, Richard D., Luyten, Yvette A., Johnson, Samuel A., Clough, Emily M., Clark, Tyson A., Roberts, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100572/
https://www.ncbi.nlm.nih.gov/pubmed/27580720
http://dx.doi.org/10.1093/nar/gkw743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100572/
https://www.ncbi.nlm.nih.gov/pubmed/27580720
http://dx.doi.org/10.1093/nar/gkw743

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