High-resolution structure of the presynaptic RAD51 filament on single-stranded DNA by electron cryo-microscopy

Homologous DNA recombination (HR) by the RAD51 recombinase enables error-free DNA break repair. To execute HR, RAD51 first forms a presynaptic filament on single-stranded (ss) DNA, which catalyses pairing with homologous double-stranded (ds) DNA. Here, we report a structure for the presynaptic human...

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Detalles Bibliográficos
Autores principales: Short, Judith M., Liu, Yang, Chen, Shaoxia, Soni, Neelesh, Madhusudhan, Mallur S., Shivji, Mahmud K.K., Venkitaraman, Ashok R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
NAR Breakthrough Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100573/
https://www.ncbi.nlm.nih.gov/pubmed/27596592
http://dx.doi.org/10.1093/nar/gkw783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100573/
https://www.ncbi.nlm.nih.gov/pubmed/27596592
http://dx.doi.org/10.1093/nar/gkw783

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