Incorporating a guanidine-modified cytosine base into triplex-forming PNAs for the recognition of a C-G pyrimidine–purine inversion site of an RNA duplex

RNA duplex regions are often involved in tertiary interactions and protein binding and thus there is great potential in developing ligands that sequence-specifically bind to RNA duplexes. We have developed a convenient synthesis method for a modified peptide nucleic acid (PNA) monomer with a guanidi...

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Detalles Bibliográficos
Autores principales: Toh, Desiree-Faye Kaixin, Devi, Gitali, Patil, Kiran M., Qu, Qiuyu, Maraswami, Manikantha, Xiao, Yunyun, Loh, Teck Peng, Zhao, Yanli, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100590/
https://www.ncbi.nlm.nih.gov/pubmed/27596599
http://dx.doi.org/10.1093/nar/gkw778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100590/
https://www.ncbi.nlm.nih.gov/pubmed/27596599
http://dx.doi.org/10.1093/nar/gkw778

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