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Long-range correlations in the mechanics of small DNA circles under topological stress revealed by multi-scale simulation

It is well established that gene regulation can be achieved through activator and repressor proteins that bind to DNA and switch particular genes on or off, and that complex metabolic networks determine the levels of transcription of a given gene at a given time. Using three complementary computatio...

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Detalles Bibliográficos
Autores principales: Sutthibutpong, Thana, Matek, Christian, Benham, Craig, Slade, Gabriel G., Noy, Agnes, Laughton, Charles, K. Doye, Jonathan P., Louis, Ard A., Harris, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100592/
https://www.ncbi.nlm.nih.gov/pubmed/27664220
http://dx.doi.org/10.1093/nar/gkw815