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Long-range correlations in the mechanics of small DNA circles under topological stress revealed by multi-scale simulation
It is well established that gene regulation can be achieved through activator and repressor proteins that bind to DNA and switch particular genes on or off, and that complex metabolic networks determine the levels of transcription of a given gene at a given time. Using three complementary computatio...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100592/ https://www.ncbi.nlm.nih.gov/pubmed/27664220 http://dx.doi.org/10.1093/nar/gkw815 |