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Sir2 regulates stability of repetitive domains differentially in the human fungal pathogen Candida albicans
DNA repeats, found at the ribosomal DNA locus, telomeres and subtelomeric regions, are unstable sites of eukaryotic genomes. A fine balance between genetic variability and genomic stability tunes plasticity of these chromosomal regions. This tuning mechanism is particularly important for organisms s...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100595/ https://www.ncbi.nlm.nih.gov/pubmed/27369382 http://dx.doi.org/10.1093/nar/gkw594 |