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Sir2 regulates stability of repetitive domains differentially in the human fungal pathogen Candida albicans

DNA repeats, found at the ribosomal DNA locus, telomeres and subtelomeric regions, are unstable sites of eukaryotic genomes. A fine balance between genetic variability and genomic stability tunes plasticity of these chromosomal regions. This tuning mechanism is particularly important for organisms s...

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Detalles Bibliográficos
Autores principales: Freire-Benéitez, Verónica, Gourlay, Sarah, Berman, Judith, Buscaino, Alessia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100595/
https://www.ncbi.nlm.nih.gov/pubmed/27369382
http://dx.doi.org/10.1093/nar/gkw594