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Identification of the mRNA targets of tRNA-specific regulation using genome-wide simulation of translation

tRNA gene copy number is a primary determinant of tRNA abundance and therefore the rate at which each tRNA delivers amino acids to the ribosome during translation. Low-abundance tRNAs decode rare codons slowly, but it is unclear which genes might be subject to tRNA-mediated regulation of expression....

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Detalles Bibliográficos
Autores principales: Gorgoni, Barbara, Ciandrini, Luca, McFarland, Matthew R., Romano, M. Carmen, Stansfield, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100601/
https://www.ncbi.nlm.nih.gov/pubmed/27407108
http://dx.doi.org/10.1093/nar/gkw630