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Using Mendelian randomization to investigate a possible causal relationship between adiposity and increased bone mineral density at different skeletal sites in children

Background: Lean mass is positively associated with bone mineral density (BMD). However, the relationship between adiposity and BMD is more controversial. In particular, it is unclear if the observational association between the two reflects a causal effect of fat mass on BMD. Previous Mendelian ran...

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Detalles Bibliográficos
Autores principales: Kemp, John P, Sayers, Adrian, Smith, George Davey, Tobias, Jonathan H, Evans, David M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100609/
https://www.ncbi.nlm.nih.gov/pubmed/27215616
http://dx.doi.org/10.1093/ije/dyw079