Selecting instruments for Mendelian randomization in the wake of genome-wide association studies

Mendelian randomization (MR) studies typically assess the pathogenic relevance of environmental exposures or disease biomarkers, using genetic variants that instrument these exposures. The approach is gaining popularity—our systematic review reveals a greater than 10-fold increase in MR studies publ...

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Detalles Bibliográficos
Autores principales: Swerdlow, Daniel I, Kuchenbaecker, Karoline B, Shah, Sonia, Sofat, Reecha, Holmes, Michael V, White, Jon, Mindell, Jennifer S, Kivimaki, Mika, Brunner, Eric J, Whittaker, John C, Casas, Juan P, Hingorani, Aroon D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Mendelian Randomization
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100611/
https://www.ncbi.nlm.nih.gov/pubmed/27342221
http://dx.doi.org/10.1093/ije/dyw088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100611/
https://www.ncbi.nlm.nih.gov/pubmed/27342221
http://dx.doi.org/10.1093/ije/dyw088

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