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Stromal Fibroblasts in Tertiary Lymphoid Structures: A Novel Target in Chronic Inflammation

Tertiary lymphoid structures (TLS) are organized aggregates of lymphocytes, myeloid, and stromal cells that provide ectopic hubs for acquired immune responses. TLS share phenotypical and functional features with secondary lymphoid organs (SLO); however, they require persistent inflammatory signals t...

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Detalles Bibliográficos
Autores principales: Barone, Francesca, Gardner, David H., Nayar, Saba, Steinthal, Nathalie, Buckley, Christopher D., Luther, Sanjiv A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100680/
https://www.ncbi.nlm.nih.gov/pubmed/27877173
http://dx.doi.org/10.3389/fimmu.2016.00477