ROCK signalling induced gene expression changes in mouse pancreatic ductal adenocarcinoma cells

The RhoA and RhoC GTPases act via the ROCK1 and ROCK2 kinases to promote actomyosin contraction, resulting in directly induced changes in cytoskeleton structures and altered gene transcription via several possible indirect routes. Elevated activation of the Rho/ROCK pathway has been reported in seve...

Descripción completa

Detalles Bibliográficos
Autores principales: Rath, Nicola, Kalna, Gabriela, Clark, William, Olson, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Data Descriptor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100681/
https://www.ncbi.nlm.nih.gov/pubmed/27824338
http://dx.doi.org/10.1038/sdata.2016.101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100681/
https://www.ncbi.nlm.nih.gov/pubmed/27824338
http://dx.doi.org/10.1038/sdata.2016.101

Ejemplares similares