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A Synthesis of Substituted α-Allenols via Iron-Catalyzed Cross-Coupling of Propargyl Carboxylates with Grignard Reagents

[Image: see text] α-Allenols are attractive and versatile compounds whose preparation can be a nontrivial task. In this Letter, we provide a method for the prompt synthesis of substituted α-allenols via a catalytic cross-coupling reaction which makes use of a nontoxic and cost-effective iron catalys...

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Detalles Bibliográficos
Autores principales: Kessler, Simon N., Hundemer, Fabian, Bäckvall, Jan-E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100686/
https://www.ncbi.nlm.nih.gov/pubmed/27840771
http://dx.doi.org/10.1021/acscatal.6b02114