Association of UGT2B7 and UGT1A4 Polymorphisms with Serum Concentration of Antiepileptic Drugs in Children

BACKGROUND: This study aimed to analyze the relationship of UGT2B7 and UGT1A4 polymorphisms with metabolism of valproic acid (VPA) and lamotrigine (LTG) in epileptic children. MATERIAL/METHODS: We administered VPA (102) and LTG (102) to 204 children with epilepsy. Blood samples were collected before...

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Detalles Bibliográficos
Autores principales: Du, Zhongliang, Jiao, Yukun, Shi, Lianting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100833/
https://www.ncbi.nlm.nih.gov/pubmed/27795544
http://dx.doi.org/10.12659/MSM.897626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100833/
https://www.ncbi.nlm.nih.gov/pubmed/27795544
http://dx.doi.org/10.12659/MSM.897626

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