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Proper Sterol Distribution Is Required for Candida albicans Hyphal Formation and Virulence

Candida albicans is an opportunistic fungus responsible for the majority of systemic fungal infections. Multiple factors contribute to C. albicans pathogenicity. C. albicans strains lacking CaArv1 are avirulent. Arv1 has a conserved Arv1 homology domain (AHD) that has a zinc-binding domain containin...

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Detalles Bibliográficos
Autores principales: McCourt, Paula, Liu, Hsing-Yin, Parker, Josie E., Gallo-Ebert, Christina, Donigan, Melissa, Bata, Adam, Giordano, Caroline, Kelly, Steven L., Nickels, Joseph T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100844/
https://www.ncbi.nlm.nih.gov/pubmed/27587298
http://dx.doi.org/10.1534/g3.116.033969