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The Smaug RNA-Binding Protein Is Essential for microRNA Synthesis During the Drosophila Maternal-to-Zygotic Transition

Metazoan embryos undergo a maternal-to-zygotic transition (MZT) during which maternal gene products are eliminated and the zygotic genome becomes transcriptionally active. During this process, RNA-binding proteins (RBPs) and the microRNA-induced silencing complex (miRISC) target maternal mRNAs for d...

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Detalles Bibliográficos
Autores principales: Luo, Hua, Li, Xiao, Claycomb, Julie M., Lipshitz, Howard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100853/
https://www.ncbi.nlm.nih.gov/pubmed/27591754
http://dx.doi.org/10.1534/g3.116.034199