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Exploring Flexibility of Progesterone Receptor Ligand Binding Domain Using Molecular Dynamics

Progesterone receptor (PR), a member of nuclear receptor (NR) superfamily, plays a vital role for female reproductive tissue development, differentiation and maintenance. PR ligand, such as progesterone, induces conformation changes in PR ligand binding domain (LBD), thus mediates subsequent gene re...

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Detalles Bibliográficos
Autores principales:	Zheng, Liangzhen, Lin, Valerie Chunling, Mu, Yuguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100906/ https://www.ncbi.nlm.nih.gov/pubmed/27824891 http://dx.doi.org/10.1371/journal.pone.0165824

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