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Exploring the Functional Complementation between Grp94 and Hsp90

Grp94 and Hsp90 are the ER and cytoplasmic paralog members, respectively, of the hsp90 family of molecular chaperones. The structural and biochemical differences between Hsp90 and Grp94 that allow each paralog to efficiently chaperone its particular set of clients are poorly understood. The two para...

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Detalles Bibliográficos
Autores principales: Maharaj, Kevin A., Que, Nanette L. S., Hong, Feng, Huck, John D., Gill, Sabrina K., Wu, Shuang, Li, Zihai, Gewirth, Daniel T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100913/
https://www.ncbi.nlm.nih.gov/pubmed/27824935
http://dx.doi.org/10.1371/journal.pone.0166271