Aortic and Cardiac Structure and Function Using High-Resolution Echocardiography and Optical Coherence Tomography in a Mouse Model of Marfan Syndrome

Marfan syndrome (MFS) is an autosomal-dominant disorder of connective tissue caused by mutations in the fibrillin-1 (FBN1) gene. Mortality is often due to aortic dissection and rupture. We investigated the structural and functional properties of the heart and aorta in a [Fbn1(C1039G/+)] MFS mouse us...

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Detalles Bibliográficos
Autores principales: Lee, Ling, Cui, Jason Z., Cua, Michelle, Esfandiarei, Mitra, Sheng, Xiaoye, Chui, Winsey Audrey, Xu, Michael Haoying, Sarunic, Marinko V., Beg, Mirza Faisal, van Breemen, Cornelius, Sandor, George G. S., Tibbits, Glen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100915/
https://www.ncbi.nlm.nih.gov/pubmed/27824871
http://dx.doi.org/10.1371/journal.pone.0164778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100915/
https://www.ncbi.nlm.nih.gov/pubmed/27824871
http://dx.doi.org/10.1371/journal.pone.0164778

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