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High-Throughput Parallel Sequencing to Measure Fitness of Leptospira interrogans Transposon Insertion Mutants during Acute Infection

Pathogenic species of Leptospira are the causative agents of leptospirosis, a zoonotic disease that causes mortality and morbidity worldwide. The understanding of the virulence mechanisms of Leptospira spp is still at an early stage due to the limited number of genetic tools available for this micro...

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Detalles Bibliográficos
Autores principales: Lourdault, Kristel, Matsunaga, James, Haake, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100919/
https://www.ncbi.nlm.nih.gov/pubmed/27824878
http://dx.doi.org/10.1371/journal.pntd.0005117