Dynamical Model of Drug Accumulation in Bacteria: Sensitivity Analysis and Experimentally Testable Predictions

We present a dynamical model of drug accumulation in bacteria. The model captures key features in experimental time courses on ofloxacin accumulation: initial uptake; two-phase response; and long-term acclimation. In combination with experimental data, the model provides estimates of import and expo...

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Detalles Bibliográficos
Autores principales: Vesselinova, Neda, Alexandrov, Boian S., Wall, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100933/
https://www.ncbi.nlm.nih.gov/pubmed/27824914
http://dx.doi.org/10.1371/journal.pone.0165899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100933/
https://www.ncbi.nlm.nih.gov/pubmed/27824914
http://dx.doi.org/10.1371/journal.pone.0165899

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