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Human Cytomegalovirus miR-UL148D Facilitates Latent Viral Infection by Targeting Host Cell Immediate Early Response Gene 5

The mechanisms underlying human cytomegalovirus (HCMV) latency remain incompletely understood. Here, we showed that a HCMV-encoded miRNA, miR-UL148D, robustly accumulates during late stages of experimental latent HCMV infection in host cells and promotes HCMV latency by modulating the immediate earl...

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Detalles Bibliográficos
Autores principales: Pan, Chaoyun, Zhu, Dihan, Wang, Yan, Li, Limin, Li, Donghai, Liu, Fenyong, Zhang, Chen-Yu, Zen, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100954/
https://www.ncbi.nlm.nih.gov/pubmed/27824944
http://dx.doi.org/10.1371/journal.ppat.1006007