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The Safety of Artemisinin Derivatives for the Treatment of Malaria in the 2nd or 3rd Trimester of Pregnancy: A Systematic Review and Meta-Analysis

Given the high morbidity for mother and fetus associated with malaria in pregnancy, safe and efficacious drugs are needed for treatment. Artemisinin derivatives are the most effective antimalarials, but are associated with teratogenic and embryotoxic effects in animal models when used in early pregn...

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Detalles Bibliográficos
Autores principales: Kovacs, Stephanie D., van Eijk, Anna Maria, Sevene, Esperanca, Dellicour, Stephanie, Weiss, Noel S., Emerson, Scott, Steketee, Richard, ter Kuile, Feiko O., Stergachis, Andy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100961/
https://www.ncbi.nlm.nih.gov/pubmed/27824884
http://dx.doi.org/10.1371/journal.pone.0164963