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The Safety of Artemisinin Derivatives for the Treatment of Malaria in the 2nd or 3rd Trimester of Pregnancy: A Systematic Review and Meta-Analysis
Given the high morbidity for mother and fetus associated with malaria in pregnancy, safe and efficacious drugs are needed for treatment. Artemisinin derivatives are the most effective antimalarials, but are associated with teratogenic and embryotoxic effects in animal models when used in early pregn...
Autores principales: | Kovacs, Stephanie D., van Eijk, Anna Maria, Sevene, Esperanca, Dellicour, Stephanie, Weiss, Noel S., Emerson, Scott, Steketee, Richard, ter Kuile, Feiko O., Stergachis, Andy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100961/ https://www.ncbi.nlm.nih.gov/pubmed/27824884 http://dx.doi.org/10.1371/journal.pone.0164963 |
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