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An Age-Associated Decline in Thymic Output Differs in Dog Breeds According to Their Longevity

The age associated decline in immune function is preceded in mammals by a reduction in thymic output. Furthermore, there is increasing evidence of a link between immune competence and lifespan. One approach to determining thymic output is to quantify signal joint T cell receptor excision circles (sj...

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Detalles Bibliográficos
Autores principales: Holder, Angela, Mella, Stephanie, Palmer, Donald B., Aspinall, Richard, Catchpole, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100965/
https://www.ncbi.nlm.nih.gov/pubmed/27824893
http://dx.doi.org/10.1371/journal.pone.0165968