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Inflammatory Bowel Disease: How Effective Is TNF-α Suppression?

Crohn’s Disease (CD) results from inappropriate response toward commensal flora. Earlier studies described CD as a Th1 mediated disease. Current models view both phenotypes as a continuum of various permutations between Th1, Th2 and Th17 pathways compounded by a range of Treg disfunctions. In the pr...

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Detalles Bibliográficos
Autores principales: Lo, Wing-Cheong, Arsenescu, Violeta, Arsenescu, Razvan I., Friedman, Avner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100971/
https://www.ncbi.nlm.nih.gov/pubmed/27824890
http://dx.doi.org/10.1371/journal.pone.0165782