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Citrullination in Rheumatoid Arthritis—A Process Promoted by Neutrophil Lysis?

Anti-citrullinated protein antibodies (ACPAs) are highly specific serologic markers for rheumatoid arthritis (RA) and can pre-date clinical disease onset by up to 10 years, also predicting erosive disease. The process of citrullination, the post-translational conversion of arginine to citrulline res...

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Detalles Bibliográficos
Autores principales: Gazitt, Tal, Lood, Christian, Elkon, Keith B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rambam Health Care Campus 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101001/
https://www.ncbi.nlm.nih.gov/pubmed/27824546
http://dx.doi.org/10.5041/RMMJ.10254