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Mitochondrial protein functions elucidated by multi-omic mass spectrometry profiling

Mitochondrial dysfunction is associated with many human diseases, including cancer and neurodegeneration, that are often linked to proteins and pathways that are not well-characterized. To begin defining the functions of such poorly characterized proteins, we used mass spectrometry to map the proteo...

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Detalles Bibliográficos
Autores principales: Stefely, Jonathan A., Kwiecien, Nicholas W., Freiberger, Elyse C., Richards, Alicia L., Jochem, Adam, Rush, Matthew J. P., Ulbrich, Arne, Robinson, Kyle P., Hutchins, Paul D., Veling, Mike T., Guo, Xiao, Kemmerer, Zachary A., Connors, Kyle J., Trujillo, Edna A., Sokol, Jacob, Marx, Harald, Westphall, Michael S., Hebert, Alexander S., Pagliarini, David J., Coon, Joshua J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101133/
https://www.ncbi.nlm.nih.gov/pubmed/27669165
http://dx.doi.org/10.1038/nbt.3683