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TCR/pMHC Interaction: Phenotypic Model for an Unsolved Enigma

TCR–pMHC interaction is the keystone of the adaptive immune response. This process exhibits an impressive capacity of speed, sensitivity, and discrimination that allows detecting foreign pMHCs at very low concentration among much more abundant self-pMHC ligands. However, and despite over three decad...

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Detalles Bibliográficos
Autores principales: Gálvez, Jesús, Gálvez, Juan J., García-Peñarrubia, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101211/
https://www.ncbi.nlm.nih.gov/pubmed/27881981
http://dx.doi.org/10.3389/fimmu.2016.00467