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Tissue-type Plasminogen Activator (tPA) Modulates the Postsynaptic Response of Cerebral Cortical Neurons to the Presynaptic Release of Glutamate

Tissue-type plasminogen activator (tPA) is a serine proteinase released by the presynaptic terminal of cerebral cortical neurons following membrane depolarization (Echeverry et al., 2010). Recent studies indicate that the release of tPA triggers the synaptic vesicle cycle and promotes the exocytosis...

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Detalles Bibliográficos
Autores principales: Jeanneret, Valerie, Wu, Fang, Merino, Paola, Torre, Enrique, Diaz, Ariel, Cheng, Lihong, Yepes, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101231/
https://www.ncbi.nlm.nih.gov/pubmed/27881952
http://dx.doi.org/10.3389/fnmol.2016.00121