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Sulforaphane Protects Pancreatic Acinar Cell Injury by Modulating Nrf2-Mediated Oxidative Stress and NLRP3 Inflammatory Pathway

Acute pancreatitis (AP) is characterized by early activation of intra-acinar proteases followed by acinar cell death and inflammation. Cellular oxidative stress is a key mechanism underlying these pathological events. Sulforaphane (SFN) is a natural organosulfur antioxidant with undescribed effects...

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Detalles Bibliográficos
Autores principales: Dong, Zhaojun, Shang, Haixiao, Chen, Yong Q., Pan, Li-Long, Bhatia, Madhav, Sun, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101394/
https://www.ncbi.nlm.nih.gov/pubmed/27847555
http://dx.doi.org/10.1155/2016/7864150