Caspase-3 Deletion Promotes Necrosis in Atherosclerotic Plaques of ApoE Knockout Mice

Apoptosis of macrophages and vascular smooth muscle cells (VSMCs) in advanced atherosclerotic plaques contributes to plaque progression and instability. Caspase-3, a key executioner protease in the apoptotic pathway, has been identified in human and mouse atherosclerotic plaques but its role in athe...

Descripción completa

Detalles Bibliográficos
Autores principales: Grootaert, Mandy O. J., Schrijvers, Dorien M., Hermans, Marthe, Van Hoof, Viviane O., De Meyer, Guido R. Y., Martinet, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101396/
https://www.ncbi.nlm.nih.gov/pubmed/27847551
http://dx.doi.org/10.1155/2016/3087469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101396/
https://www.ncbi.nlm.nih.gov/pubmed/27847551
http://dx.doi.org/10.1155/2016/3087469

Ejemplares similares