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SGTA interacts with the proteasomal ubiquitin receptor Rpn13 via a carboxylate clamp mechanism
The fate of secretory and membrane proteins that mislocalize to the cytosol is decided by a collaboration between cochaperone SGTA (small, glutamine-rich, tetratricopeptide repeat protein alpha) and the BAG6 complex, whose operation relies on multiple transient and subtly discriminated interactions...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101480/ https://www.ncbi.nlm.nih.gov/pubmed/27827410 http://dx.doi.org/10.1038/srep36622 |