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Molecular basis for epitope recognition by non-neutralizing anti-gp41 antibody F240

Antibody-dependent cell-mediated cytotoxicity (ADCC) by non-neutralizing antibodies (nnAbs) specific to the HIV envelope (Env) glycoproteins present at the surface of virus sensitized or infected cells plays a role in the effective adaptive immune response to HIV. Here, we explore the molecular basi...

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Detalles Bibliográficos
Autores principales: Gohain, Neelakshi, Tolbert, William D., Orlandi, Chiara, Richard, Jonathan, Ding, Shilei, Chen, Xishan, Bonsor, Daniel A., Sundberg, Eric J., Lu, Wuyuan, Ray, Krishanu, Finzi, Andrés, Lewis, George K., Pazgier, Marzena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101508/
https://www.ncbi.nlm.nih.gov/pubmed/27827447
http://dx.doi.org/10.1038/srep36685