Hydrogen peroxide induced loss of heterozygosity correlates with replicative lifespan and mitotic asymmetry in Saccharomyces cerevisiae

Cellular aging in Saccharomyces cerevisiae can lead to genomic instability and impaired mitotic asymmetry. To investigate the role of oxidative stress in cellular aging, we examined the effect of exogenous hydrogen peroxide on genomic instability and mitotic asymmetry in a collection of yeast strain...

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Detalles Bibliográficos
Autores principales: Güven, Emine, Parnell, Lindsay A., Jackson, Erin D., Parker, Meighan C., Gupta, Nilin, Rodrigues, Jenny, Qin, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2016
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101604/
https://www.ncbi.nlm.nih.gov/pubmed/27833823
http://dx.doi.org/10.7717/peerj.2671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101604/
https://www.ncbi.nlm.nih.gov/pubmed/27833823
http://dx.doi.org/10.7717/peerj.2671

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