Binding of galectin-1 to breast cancer cells MCF7 induces apoptosis and inhibition of proliferation in vitro in a 2D- and 3D- cell culture model

BACKGROUND: Galectin-1 (gal-1) belongs to the family of β-galactoside-binding proteins which primarily recognizes the Galβ1-4GlcNAc sequences of oligosaccharides associated with several cell surface glycoconjugates. The lectin recognizes correspondent glycoepitopes on human breast cancer cells. Gale...

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Detalles Bibliográficos
Autores principales: Geiger, Pamina, Mayer, Barbara, Wiest, Irmi, Schulze, Sandra, Jeschke, Udo, Weissenbacher, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101677/
https://www.ncbi.nlm.nih.gov/pubmed/27825375
http://dx.doi.org/10.1186/s12885-016-2915-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101677/
https://www.ncbi.nlm.nih.gov/pubmed/27825375
http://dx.doi.org/10.1186/s12885-016-2915-8

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