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Non-neuronal cholinergic system contributes to corticosteroid resistance in chronic obstructive pulmonary disease patients

BACKGROUND: Inhaled corticosteroid (ICS) with long-acting beta-2 agonists is a well-documented combination therapy for chronic obstructive pulmonary disease (COPD) based on its additive anti-inflammatory properties. By contrast, the recommendation of ICS in combination with long-acting muscarinic an...

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Detalles Bibliográficos
Autores principales: Milara, Javier, Cervera, Angela, de Diego, Alfredo, Sanz, Celia, Juan, Gustavo, Gavaldà, Amadeu, Miralpeix, Montserrat, Morcillo, Esteban, Cortijo, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101693/
https://www.ncbi.nlm.nih.gov/pubmed/27825347
http://dx.doi.org/10.1186/s12931-016-0467-8