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L-BSE experimentally transmitted to sheep presents as a unique disease phenotype

Apart from prion protein genotype, the factors determining the host range and susceptiblity for specific transmissible spongiform encephalopathy agents remain unclear. It is known that bovine atypical L-BSE can transmit to a range of species including primates and humanised transgenic mice. It is im...

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Detalles Bibliográficos
Autores principales: Simmons, Marion M., Chaplin, Melanie J., Konold, Timm, Casalone, Cristina, Beck, Katy E., Thorne, Leigh, Everitt, Sharon, Floyd, Tobias, Clifford, Derek, Spiropoulos, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101820/
https://www.ncbi.nlm.nih.gov/pubmed/27825366
http://dx.doi.org/10.1186/s13567-016-0394-1