Gap junction inhibition by heptanol increases ventricular arrhythmogenicity by reducing conduction velocity without affecting repolarization properties or myocardial refractoriness in Langendorff-perfused mouse hearts

In the current study, arrhythmogenic effects of the gap junction inhibitor heptanol (0.05 mM) were examined in Langendorff-perfused mouse hearts. Monophasic action potential recordings were obtained from the left ventricular epicardium during right ventricular pacing. Regular activity was observed b...

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Detalles Bibliográficos
Autores principales: Tse, Gary, Yeo, Jie Ming, Tse, Vivian, Kwan, Joseph, Sun, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101880/
https://www.ncbi.nlm.nih.gov/pubmed/27633494
http://dx.doi.org/10.3892/mmr.2016.5738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101880/
https://www.ncbi.nlm.nih.gov/pubmed/27633494
http://dx.doi.org/10.3892/mmr.2016.5738

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