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Glycogen synthase kinase-3β is required for epithelial-mesenchymal transition and barrier dysfunction in mouse podocytes under high glucose conditions

Epithelial-mesenchymal transition (EMT) is important for diabetic nephropathy (DN). Podocytes are specialized epithelial cells, which form a major component of the glomerular filtration barrier. Podocyte damage has been suggested to be the primary mechanism behind the albuminuria associated with DN....

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Detalles Bibliográficos
Autores principales: Guo, Jia, Yang, Lili, Qiao, Yingjin, Liu, Zhangsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101890/
https://www.ncbi.nlm.nih.gov/pubmed/27748847
http://dx.doi.org/10.3892/mmr.2016.5786