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Trimetazidine protects against cardiac ischemia/reperfusion injury via effects on cardiac miRNA-21 expression, Akt and the Bcl-2/Bax pathway

Trimetazidine is a piperazine-derived metabolic agent, which exerts cell protective effects and has been reported to be efficient in the treatment of chronic stable angina pectoris. In addition, it has been shown to exert protection against acute myocardial infarction. The present study aimed to inv...

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Detalles Bibliográficos
Autores principales: Ma, Ning, Bai, Jingyun, Zhang, Weihua, Luo, Hong, Zhang, Xin, Liu, Donghai, Qiao, Chenhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101925/
https://www.ncbi.nlm.nih.gov/pubmed/27666568
http://dx.doi.org/10.3892/mmr.2016.5773