Cooperative enhancement of deoxyribozyme activity by chemical modification and added cationic copolymer

Deoxyribozymes (DNAzymes) having RNA-cleaving activity have widely been explored as tools for therapeutic and diagnostic purposes. Both the chemical cleaving step and the turnover step should be improved for enhancing overall activity of DNAzymes. We have shown that cationic copolymer enhanced DNAzy...

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Detalles Bibliográficos
Autores principales: Saito, Ken, Shimada, Naohiko, Maruyama, Atushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Focus on Nanomedicine molecular science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102035/
https://www.ncbi.nlm.nih.gov/pubmed/27877894
http://dx.doi.org/10.1080/14686996.2016.1208627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102035/
https://www.ncbi.nlm.nih.gov/pubmed/27877894
http://dx.doi.org/10.1080/14686996.2016.1208627

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