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Cooperative enhancement of deoxyribozyme activity by chemical modification and added cationic copolymer
Deoxyribozymes (DNAzymes) having RNA-cleaving activity have widely been explored as tools for therapeutic and diagnostic purposes. Both the chemical cleaving step and the turnover step should be improved for enhancing overall activity of DNAzymes. We have shown that cationic copolymer enhanced DNAzy...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102035/ https://www.ncbi.nlm.nih.gov/pubmed/27877894 http://dx.doi.org/10.1080/14686996.2016.1208627 |