The Human Kinome Targeted by FDA Approved Multi-Target Drugs and Combination Products: A Comparative Study from the Drug-Target Interaction Network Perspective

The human kinome is one of the most productive classes of drug target, and there is emerging necessity for treating complex diseases by means of polypharmacology (multi-target drugs and combination products). However, the advantages of the multi-target drugs and the combination products are still un...

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Detalles Bibliográficos
Autores principales: Li, Ying Hong, Wang, Pan Pan, Li, Xiao Xu, Yu, Chun Yan, Yang, Hong, Zhou, Jin, Xue, Wei Wei, Tan, Jun, Zhu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102354/
https://www.ncbi.nlm.nih.gov/pubmed/27828998
http://dx.doi.org/10.1371/journal.pone.0165737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102354/
https://www.ncbi.nlm.nih.gov/pubmed/27828998
http://dx.doi.org/10.1371/journal.pone.0165737

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