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Hyperthermia Influences the Effects of Sodium Channel Blocking Drugs in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes

INTRODUCTION: Fever can increase the susceptibility to supraventricular and ventricular arrhythmias, in which sodium channel dysfunction has been implicated. Whether fever influences the efficacy of sodium channel blocking drugs is unknown. The current study was designed to investigate the temperatu...

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Detalles Bibliográficos
Autores principales: El-Battrawy, Ibrahim, Lang, Siegfried, Zhao, Zhihan, Akin, Ibrahim, Yücel, Gökhan, Meister, Sophie, Patocskai, Bence, Behnes, Michael, Rudic, Boris, Tülümen, Erol, Liebe, Volker, Tiburcy, Malte, Dworacek, Jennifer, Zimmermann, Wolfram-Hubertus, Utikal, Jochen, Wieland, Thomas, Borggrefe, Martin, Zhou, Xiao-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102382/
https://www.ncbi.nlm.nih.gov/pubmed/27829006
http://dx.doi.org/10.1371/journal.pone.0166143