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Aberrant Collagen Composition of the Trabecular Meshwork Results in Reduced Aqueous Humor Drainage and Elevated IOP in MMP-9 Null Mice

PURPOSE: Homeostatic turnover of the trabecular meshwork extracellular matrix (ECM) is essential to regulate aqueous humor outflow and to maintain intraocular pressure homeostasis. In this study, we evaluated aqueous humor turnover, intraocular pressure, and trabecular meshwork organization in MMP-9...

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Detalles Bibliográficos
Autores principales: De Groef, Lies, Andries, Lien, Siwakoti, Anuja, Geeraerts, Emiel, Bollaerts, Ilse, Noterdaeme, Lut, Etienne, Isabelle, Papageorgiou, Anna-Pia, Stalmans, Ingeborg, Billen, Johan, West-Mays, Judith A., Moons, Lieve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102567/
https://www.ncbi.nlm.nih.gov/pubmed/27820954
http://dx.doi.org/10.1167/iovs.16-19734