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Aberrant Collagen Composition of the Trabecular Meshwork Results in Reduced Aqueous Humor Drainage and Elevated IOP in MMP-9 Null Mice
PURPOSE: Homeostatic turnover of the trabecular meshwork extracellular matrix (ECM) is essential to regulate aqueous humor outflow and to maintain intraocular pressure homeostasis. In this study, we evaluated aqueous humor turnover, intraocular pressure, and trabecular meshwork organization in MMP-9...
Autores principales: | De Groef, Lies, Andries, Lien, Siwakoti, Anuja, Geeraerts, Emiel, Bollaerts, Ilse, Noterdaeme, Lut, Etienne, Isabelle, Papageorgiou, Anna-Pia, Stalmans, Ingeborg, Billen, Johan, West-Mays, Judith A., Moons, Lieve |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102567/ https://www.ncbi.nlm.nih.gov/pubmed/27820954 http://dx.doi.org/10.1167/iovs.16-19734 |
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